Back پریتینول AZB Pyritinol German Piritinol Spanish پیریتینول Persian Piritinol ID ピリチノール Japanese Pyritinol Polish Piritinol Romanian Пиритинол Russian Piritinol Serbo-Croatian

Pyritinol

Pyritinol
Clinical data
ATC code
Pharmacokinetic data
Elimination half-life2.5 hours
Identifiers
  • 5,5'-[dithiobis(methylene)]bis[4-(hydroxymethyl)-2-methylpyridin-3-ol]
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.012.864 Edit this at Wikidata
Chemical and physical data
FormulaC16H20N2O4S2
Molar mass368.47 g·mol−1
3D model (JSmol)
  • Oc1c(c(cnc1C)CSSCc2c(c(O)c(nc2)C)CO)CO
  • InChI=1S/C16H20N2O4S2/c1-9-15(21)13(5-19)11(3-17-9)7-23-24-8-12-4-18-10(2)16(22)14(12)6-20/h3-4,19-22H,5-8H2,1-2H3 checkY
  • Key:SIXLXDIJGIWWFU-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Pyritinol also called pyridoxine disulfide or pyrithioxine (European drug names Encephabol, Encefabol, Cerbon 6) is a semi-synthetic water-soluble analog of vitamin B6 (Pyridoxine HCl). It was produced in 1961 by Merck Laboratories by bonding 2 vitamin B6 compounds (pyridoxine) together with a disulfide bridge. Since the 1970s, it has been a prescription and OTC drug in several countries for cognitive disorders, rheumatoid arthritis,[1] and learning disorders in children. Since the early 1990s it has been sold as a nootropic dietary supplement in the United States.

  1. ^ Lemmel EM (May 1993). "Comparison of pyritinol and auranofin in the treatment of rheumatoid arthritis. The European Multicentre Study Group". British Journal of Rheumatology. 32 (5): 375–82. doi:10.1093/rheumatology/32.5.375. PMID 8495257.
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